High Institute of Public Health, Alexandria UniversityJournal of High Institute of Public Health2357-060143120130401Prevalence of Methicillin Resistant Staphylococcus aureus Nasal Carriage and its Antibiogram in Healthcare Workers from South of Jordan1121998410.21608/jhiph.2013.19984ENHamed AlzoubiMedical Microbiology and Immunology Department, Faculty of Medicine, Mu'tah University, Alkarak, JordanAmin AqelMedical Microbiology and Immunology Department, Faculty of Medicine, Mu'tah University, Alkarak, JordanMunir Abu-HelalahDepartment of Public Health, Faculty of Medicine, Mu'tah University, Alkarak, JordanJournal Article20181128 <br /> Background: <span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Healthcare workers (HCWs) can act as asymptomatic carriers in transmitting Methicillin Resistant Staphylococcus aureus (MRSA). Availability of epidemiological and antibiotic susceptibility data is necessary to limit the spread of HCWs-associated MRSA infections, and to help physicians in choosing the appropriate empirical antibiotic for management of such infections. <strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Objective: </span></span></strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">to assess nasal carriage and antibiogram of MRSA in healthcare workers from Southern Jordan<span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">. <strong>Methods:</strong> <span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">a total of 276 nasal swabs were randomly collected from the HCWs. </span></span></span></span><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">MRSA was identified </span></span></span></span><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">by culture, biochemical and</span></span></span></span><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;"> molecular methods. Antibiotic susceptibility was determined by the disc diffusion method<span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">. <strong>Results:</strong> </span></span><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">The HCWs-MRSA nasal carriage was 8.7%. There was significant difference for nasal carriage of MRSA by nurse occupation (<em><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">p </span></span></em><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">value = 0.007), education level of less than a university degree (<em><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">p </span></span></em><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">value = 0.039) and years of HCW experience (</span></span><em><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">p </span></span></em><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">value = 0.023). No significant difference by age, sex, antibiotic exposure or smoking. Antibiotic resistance to Trimethoprim-Sulfamethoxazole and Tetracycline was detected in 37.5% and 12.5% of all MRSA isolates respectively. No resistance to the other antibiotics used in this study and no multidrug resistance was encountered in all MRSA isolates. <strong>C</strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;"><strong>onclusion:</strong> </span></span><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">MRSA nasal carriage among HCWs in this study was 8.7% with no alarming antibiotic resistance pattern. Nurses, less educated and more experienced HCWs are at increased risk of MRSA nasal carriage. Therefore, we strongly recommend screening and decolonizing positive HCWs who can act as asymptomatic carriers in MRSA transmission cycle.</span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span>High Institute of Public Health, Alexandria UniversityJournal of High Institute of Public Health2357-060143120130401Pilot Screening of Acrylamide Level in Some Egyptian Brands of Potato and Corn Products13211998510.21608/jhiph.2013.19985ENNeveen AgamyDepartment of Nutrition, Food Analysis Division, High Institute of Public Health,
Alexandria University, Alexandria, EgyptJournal Article20181128Background<span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">: <span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Acrylamide is a chemical compound produced in starchy foods that have been cooked at high temperatures. Acrylamide is proven to be carcinogenic in rodents and a probable human carcinogen, with increasing evidence of positive associations with human cancers. Acrylamide is formed in potato crisps, chips, bread and crisp bread. It was first discovered by scientists in Sweden in 2002. <strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Objective</span></span><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">: </span></span></strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">To determine the level of acrylamide in popular Egyptian brands of potato crisps and corn products produced by domestic food industrial factories. <strong><span style="color: #494949; font-family: Arial; font-size: xx-small;"><span style="color: #494949; font-family: Arial; font-size: xx-small;"><span style="color: #494949; font-family: Arial; font-size: xx-small;">Methods</span></span></span><span style="color: #494949; font-family: Arial; font-size: xx-small;"><span style="color: #494949; font-family: Arial; font-size: xx-small;"><span style="color: #494949; font-family: Arial; font-size: xx-small;">: </span></span></span></strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Seven brands of potato and eight brands of corn products were collected, crashed and after preparing the extracts of each sample, high performance liquid chromatography (HPLC) was used for measuring the amount of acrylamide. <strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Results</span></span><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">: </span></span></strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">The amounts of acrylamide ranged 247–1677μg/kg in potato brands and <35–419μg/kg in corn products. <strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Conclusion</span></span><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">: </span></span></strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">As acrylamide is a dangerous toxin for human health, its level in these products, that are used extensively by people especially children, should be strictly traced and reduced.</span></span></span></span></span></span></span></span></span></span></span></span>High Institute of Public Health, Alexandria UniversityJournal of High Institute of Public Health2357-060143120130401The Effect of Training of School Physicians on their Knowledge Regarding Surveillance in Alexandria22351998610.21608/jhiph.2013.19986ENNessrin El-NimrEpidemiology Department, High Institute of Public Health, Alexandria University, EgyptIman WahdanEpidemiology Department, High Institute of Public Health, Alexandria University, EgyptJournal Article20181128Background: <span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Surveillance is important in schools. Training of school health physicians on surveillance is recommended in order to improve the disease surveillance system. The aim of the current study is to assess the effect of a training program on the knowledge of school physicians regarding surveillance. M<strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">ethods</span></span></strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">: Seventy school health physicians from all Health Insurance Organization districts were included in the study. Assessment of their baseline knowledge regarding surveillance was done using a pre-designed self-administered structured questionnaire (pretest). Accordingly, an intervention program in the form of a workshop was prepared to raise their knowledge regarding surveillance. Within one week after the end of the intervention, assessment of the training program was done using the same data collection tool (post -test). <strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Results: </span></span></strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">After the intervention, the percentage of physicians with poor and fair knowledge levels regarding surveillance decreased from 37.4% to 10.4% and from 50.7% to 40.3% respectively, while those with good knowledge level increased from 11.9% to 49.3%.The difference in the mean knowledge score before and after the intervention was statistically significant. In a multiple linear regression model, two factors significantly affected the school physicians’ knowledge score after the intervention. These factors were the total knowledge score before the intervention and the physicians' age. <strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Conclusion</span></span></strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">: Training of school physicians on disease surveillance affectstheir level of knowledge regarding surveillancewhich is essential for planning and evaluation of communicable diseases' prevention and control.</span></span></span></span></span></span></span></span>High Institute of Public Health, Alexandria UniversityJournal of High Institute of Public Health2357-060143120130401Measles and Rubella Vaccine Antibody Levels in Children with Acute Lymphoblastic Leukemia Following Chemotherapy36481998710.21608/jhiph.2013.19987ENHeba SelimMicrobiology Department, High Institute of Public Health, Alexandria University, Alexandria, EgyptSoraya El ShazlyMicrobiology Department, High Institute of Public Health, Alexandria University, Alexandria, EgyptMostafa SalamaPediatric Department, Faculty of Medicine, Alexandria University, Alexandria, EgyptReham AbdolmonemMicrobiology Department, High Institute of Public Health, Alexandria University, Alexandria, EgyptJournal Article20181128Background: <span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Children in remission from acute lymphoblastic leukemia (ALL) have a high prevalence of immune system defects; one of them is the decrease of vaccine-induced antibody seropositivity rates. This antibody deficiency may place children with ALL at risk for the development of vaccine- preventable diseases, even after completion of chemotherapy, and they could function as a reservoir for additional spread of these diseases in the population. The aim of the present study was the assessment of the levels of vaccine- induced antibodies against measles and rubella viruses in ALL children following chemotherapy. M<strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">ethods: </span></span></strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Antibody levels against measles and rubella vaccine viruses were evaluated by ELISA technique in 96 children with ALL after completion of chemotherapy, in addition to 30 healthy children (non cancer controls of matched age and sex). <strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Results: </span></span></strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">All healthy children were seropositive for measles and rubella antibodies.On the other hand, out of 96 children who received chemotherapy, only 19 (19.8%) were seropositive for measles antibodies, while 70 (72.9%) were seropositive for rubella antibodies. Most of measles seropositive cases (57.9%) had low levels of measles antibodies while among control group most children (56.7%) had high levels of measles antibodies. Similarly among children who received chemotherapy, most of the seropositive cases (45.7%) had low levels of rubella antibodies, while among control group, most of children (36.6%) had high levels of rubella antibodies. Seropositivity rate of measles was found to be related to the age at diagnosis and disease duration, while that of rubella was found to be related to the disease duration only. <strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Conclusion and recommendations</span></span></strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">: Most of children who have been treated with chemotherapy for ALL had lost measles antibodies and to less extent rubella antibodies. Among seropositive cases, levels of measles and rubella antibodies are low following treatment with chemotherapy compared to levels among normal controls. Therefore, revaccination of children with ALL following completion of chemotherapeutic treatment against measles and rubella is recommended.</span></span></span></span></span></span></span></span>High Institute of Public Health, Alexandria UniversityJournal of High Institute of Public Health2357-060143120130401Characteristics of Polycythemia in Sana'a, Yemen49571998810.21608/jhiph.2013.19988ENHafiz Al-NoodDepartment of Hematology, Faculty of Medicine and Health Sciences, Sana’a University, Sana’a, YemenLutfi Al-MaktariDepartment of Hematology, Faculty of Medicine and Health Sciences, Sana’a University, Sana’a, YemenJournal Article20181128Background: <span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">High altitude polycythemia is one of the altitude illnesses. Sana'a region is located at high altitudewhich reaches 3600 meters above the sea level. <strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Objectives: </span></span></strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">To determine the hematological and clinical features of polycythemic patients residingin Sana'a region and to clarify the effect of high altitude in causing polycythemia. <strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Methods: </span></span></strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Hematological, clinical and demographic data were obtained from 30 polycythemic patients (26 males, 4 females, aged 26 to 85 years residing Sana'a regionand referred to the National Centre of Public Health Laboratories in Sana'a city for the firsttime venesection. R<strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">esults:</span></span></strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">All studied samples showed high hemoglobinlevels (mean 18.85 g/dL for both sexes), normal platelet counts (228 and 267 x10 <span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">9</span></span><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">/L for males and females, respectively),normal white cell counts in 96.7% of the cases (means 6.01 to 5.98 x10 <span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">9</span></span><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">/L). Their clinical features showed predominance of headache, ruddy cyanosis, dyspnea and night sweating by 86.7%, 76.7%, 70% and 60%, respectively. Hypertension, joint pain, renal disease, peptic ulcer were less commonly mentioned by 36.7%, 20%, 13.3%, and10%, respectively. Hemorrhage, pruritus, splenomegaly, heart disease andliver disease wereobserved by only 6.67% each. <strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Conclusions: </span></span></strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Findings suggest thatsecondary polycythemia is predominant among polycythemicpatients due to the high altitude of Sana’a region. Findings needs to be confirmed bystudyinga larger sample and extended to investigate the erythropoietin level and JAK2V617F mutation for accurate diagnosis.</span></span></span></span></span></span></span></span></span></span></span></span></span></span>High Institute of Public Health, Alexandria UniversityJournal of High Institute of Public Health2357-060143120130401Effect of Chickpea Substitute on the Quality Characteristics of Biscuits and Cake58741998910.21608/jhiph.2013.19989ENNabil El-ShimyFaculty of Tourism & Hotel Management – Pharos University, Alexandria, EgyptJournal Article20181128Background: <span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Chickpea (Cicer arietinum L.) is considered the fifth valuable legume in terms of worldwide economic stand point. It is planted in southern and western area of Asia and Mediterranean.<strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;"> </span></span><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Objective: </span></span></strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">This study was undertaken to study the effect of supplementation of wheat flour with different percentages of chickpea (5, 10, 15, 20, 30 %) on the chemical composition, physical and organoleptic properties of biscuits and cakes. <strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Methods: </span></span></strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Cake and biscuits were prepared using different percentage of chickpea flour. Substitute the wheat flour in their formula. Chemical composition, physical measurements as well as sensory evaluation were carried out on the tested samples. <strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Results: </span></span></strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">The results showed that chickpea flour is a good source of protein (22.82%), crude fiber <strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">(</span></span></strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">2.90%) and ash (3.33%). Also, chickpea is rich in potassium, magnesium and iron. Supplementation of wheat flour with chickpea flours in biscuits results in increasing protein, lipid, fiber and ash. The specific volume were in the range of (38.83 – 44.13cc/gm), specific lightness were in the range of (41-25 cc/gm.) and spread factor ranged between (100-114.21%) for control samples and biscuits that contain 30 % of the chick pea flour. This biscuit which contain chickpea flour at all the supplement ratio were accepted by the panelist. The cake prepared with supplementation of wheat flour with chickpea flours at different percentage (5, 10, 15, 20, 30%) had a higher protein, lipid, crude fiber and ash content with less percentage of carbohydrates. Increasing the ratio of chickpea flours in cake has led to a slight increase in volume and specific gravity. Sensory evaluation of the cake was accepted at all the different supplementation ratios of chickpea with the higher score for the cake samples that contain chickpea flours at ratio 10 -15%. <strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Conclusion: </span></span></strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Generally prepared cake and biscuits samples with chickpea flour as a supplement to wheat flour in their formula lead to increasing protein, crude fiber and mineral content with improving the physical properties and organoleptic characteristics.</span></span></span></span></span></span></span></span></span></span></span></span>High Institute of Public Health, Alexandria UniversityJournal of High Institute of Public Health2357-060143120130401Maternal and Fetal Leptin Level Correlation with Fetal Macrosomia75821999010.21608/jhiph.2013.19990ENManal SwelemDepartment of Obstetrics & Gynecology, El-Shatby University Hospital, Alexandria, EgyptYasser ElkassarDepartment of Obstetrics & Gynecology, El-Shatby University Hospital, Alexandria, EgyptAbd Elmoneim FawzyDepartment of Obstetrics & Gynecology, El-Shatby University Hospital, Alexandria, EgyptAhmed Abd ElattyDepartment of Obstetrics & Gynecology, El-Shatby University Hospital, Alexandria, EgyptAkram DeghadyDepartment of clinical and chemical pathology Alexandria University, Alexandria, EgyptJournal Article20181128Background: <span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Leptin seems to be a critical factor for overall fetal development. Macrosomia may place the mother and fetus or neonate at risk for adverse outcomes. <strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Objective: </span></span></strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">to test if leptin level is implicated in macrosomia. <strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Methods: </span></span></strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">The sample comprised25 cases delivered full term normal weight infants, and 25 cases delivered full term macrosomicinfants. Maternal serum samples and fetal cord samples were withdrawn immediately after birth of the full term infants. <strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Results</span></span></strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">: Fetal leptin level was higher in macrosomic infants than normal weight infants. No difference in maternal leptin level between both groups was observed. <strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">Conclusion</span></span></strong><span style="font-family: Arial; font-size: xx-small;"><span style="font-family: Arial; font-size: xx-small;">: Leptin levels related directly to quantity of body fat tissue in fetal macrosomia as there is leptinresistence causing elevated leptin evels.</span></span></span></span></span></span></span></span></span></span>High Institute of Public Health, Alexandria UniversityJournal of High Institute of Public Health2357-060143120130401The Oxidative Stress and Platelet Activation in Patients Infected with Toxoplasma gondii83971999110.21608/jhiph.2013.19991ENHoda HamdyDepartments of Biochemistry; Medical Research Institute, Alexandria University, Alexandria, EgyptMona ElSayedDepartments of Parasitology; Medical Research Institute, Alexandria University, Alexandria, EgyptNadia SadekDepartments of Hematology; Medical Research Institute, Alexandria University, Alexandria, EgyptReem ElhammamyDepartments of Pharmacist in Ministry of Health Medical Research Institute, Alexandria University, Alexandria, EgyptJournal Article20181128<strong>Background: </strong><em>Toxoplasma gondii </em>is a highly frequent obligate intracellular protozoan parasite; it can cause serious problems to the public health especially pregnant females, however, the pathogenesis of this condition is not clear. <strong>Objective: </strong>was to evaluate the status and the inter-relationship of the oxidative stress and platelet activation in patients infected with <em>T. gondii</em>. <strong>Methods: </strong>Thirty patients infected with <em>T.gondii </em>(10 acute and 20 chronic cases) and 10 healthy subjects (control group) were included in this study. Serum levels of malondialdehyde (MDA), total glutathione (t GSH), reduced glutathione (GSH), oxidized glutathione (GSSG), redox potential (RP) and soluble P-selectin (sPselectin) were measured. EDITA blood samples were used for complete blood picture with special emphasis on platelet count and mean platelet volume (MPV). <strong>Results: </strong>The mean platelet volume (MPV) in patients was significantly higher than the control group, however, platelet count showed no significant difference. The serum mean values of MDA, GSSG, RP and sP-selectin in patients were significantly higher than the control subjects. On the other hand, the levels of tGSH and GSHin patients were significantly lower than in controls. MPV and platelet count showed significant positive correlations with sP-selectin concentration. <strong>Conclusion</strong>: Although toxoplasmosis is mostly asymptomatic, the findings of the present study strongly indicate that the occurrence of oxidative stress could be a potential mechanism of subclinical inflammatory pathology and tissue damage in these cases.