Barakat, K., Tadros, H. (2009). In Vitro Antibacterial Activity from Marine Algal Extracts Against Virulent Bacteria. Journal of High Institute of Public Health, 39(3), 432-448. doi: 10.21608/jhiph.2009.20845
Khouloud Barakat; Hermine Tadros. "In Vitro Antibacterial Activity from Marine Algal Extracts Against Virulent Bacteria". Journal of High Institute of Public Health, 39, 3, 2009, 432-448. doi: 10.21608/jhiph.2009.20845
Barakat, K., Tadros, H. (2009). 'In Vitro Antibacterial Activity from Marine Algal Extracts Against Virulent Bacteria', Journal of High Institute of Public Health, 39(3), pp. 432-448. doi: 10.21608/jhiph.2009.20845
Barakat, K., Tadros, H. In Vitro Antibacterial Activity from Marine Algal Extracts Against Virulent Bacteria. Journal of High Institute of Public Health, 2009; 39(3): 432-448. doi: 10.21608/jhiph.2009.20845
In Vitro Antibacterial Activity from Marine Algal Extracts Against Virulent Bacteria
1Marine Microbiology Lab., Division of Marine Environment, National Institute of Oceanography & Fisheries, Alexandria, Egypt
2Marine Chemistry Lab., Division of Marine Environment, National Institute of Oceanography & Fisheries, Alexandria, Egypt
Abstract
In vitro screening using methanolic extracts of different marine algae and one sea grass showed antibacterial activity against eight virulent strains of fish and human pathogens. 1:1 (V: V) ratios of each methanolic extract were mutually added to give 21 interactions. The interaction between Udotea sp and Codium fragile extracts exhibited higher activities against Edwardsiella tarda (18±0.9mm), Vibrio ordalli (16±0.8mm), Klebsiella pneumonia (20±1mm) and Pseudomonas aeruginosa (16±0.8mm). The bioactivity of this interaction was found to be more effective than that obtained from some common antibiotics including: Lincolin, Streptomycin and Gentamycin. The chemical constituents of these two algal extracts and their interaction were characterized using thin layer chromatography and gas chromatographic – mass spectral analysis. The bioactivity of the separated compounds was estimated. Palmitic acid was the most active fatty acid.