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Moussa, F., Abou Samara, W., El-Masry, A. (2000). Effect of Acute Zinc Administration on Essential Metal Levels in Liver, Kidney, Lung and Heart of the Male Egyptian Toad Bufo Regularis. Journal of High Institute of Public Health, 30(3), 473-480. doi: 10.21608/jhiph.2000.252702
F I. Moussa; W Abou Samara; A A. El-Masry. "Effect of Acute Zinc Administration on Essential Metal Levels in Liver, Kidney, Lung and Heart of the Male Egyptian Toad Bufo Regularis". Journal of High Institute of Public Health, 30, 3, 2000, 473-480. doi: 10.21608/jhiph.2000.252702
Moussa, F., Abou Samara, W., El-Masry, A. (2000). 'Effect of Acute Zinc Administration on Essential Metal Levels in Liver, Kidney, Lung and Heart of the Male Egyptian Toad Bufo Regularis', Journal of High Institute of Public Health, 30(3), pp. 473-480. doi: 10.21608/jhiph.2000.252702
Moussa, F., Abou Samara, W., El-Masry, A. Effect of Acute Zinc Administration on Essential Metal Levels in Liver, Kidney, Lung and Heart of the Male Egyptian Toad Bufo Regularis. Journal of High Institute of Public Health, 2000; 30(3): 473-480. doi: 10.21608/jhiph.2000.252702

Effect of Acute Zinc Administration on Essential Metal Levels in Liver, Kidney, Lung and Heart of the Male Egyptian Toad Bufo Regularis

Article 5, Volume 30, Issue 3, July 2000, Page 473-480  XML
Document Type: Original Article
DOI: 10.21608/jhiph.2000.252702
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Authors
F I. Moussa1; W Abou Samara2; A A. El-Masry1
1Zoology Department, Faculty of Science, Alexandria University, Egypt
2Biology Department, Faculty of Education, Alexandria University, Egypt
Abstract
To compare the organ injuries by Zn2+ a concentration of 48 mg Zn/kg body weight which represents to LD50 was administered intramuscularlly to the male Egyptian toad Buflo regulasis. Median lethal concentration values [LD50] were 68, 62, 54 & 48 mg Zn/kg body weight for 24, 48, 72 and 96 hr respectively. The changes in the concentration of 6 essential metals [Zn, Fe, Cu, Ca, Mg & Mn] were determind in liver, kidney, heart and lung of he male Egyptian toad Bufo regularis. Marked alterations in hepatic metal levels [increases of Zn, Cu & Ca accompanied by a decrease in Fe content were observed. Renal Zn and Cu Concentrations were increased while renal magnesium was decreased. A significant depletion in Mg content was observed in the heart of the treated toad, while Mn content was increased in the lung of the treated toad.
Keywords
Toad; Zinc; Calcium; Copper
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