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Volume Volume 29 (1999)
El-Ghandour, A., El-Sorady, M., Abdelaziz, A., El Bordini, M. (1999). Level of Basic Fibroblast Growth Factor in Breast Cancer Patients. Journal of High Institute of Public Health, 29(4), 725-730. doi: 10.21608/jhiph.1999.325380
Ashraf El-Ghandour; Manal El-Sorady; Amr Abdelaziz; Magdy El Bordini. "Level of Basic Fibroblast Growth Factor in Breast Cancer Patients". Journal of High Institute of Public Health, 29, 4, 1999, 725-730. doi: 10.21608/jhiph.1999.325380
El-Ghandour, A., El-Sorady, M., Abdelaziz, A., El Bordini, M. (1999). 'Level of Basic Fibroblast Growth Factor in Breast Cancer Patients', Journal of High Institute of Public Health, 29(4), pp. 725-730. doi: 10.21608/jhiph.1999.325380
El-Ghandour, A., El-Sorady, M., Abdelaziz, A., El Bordini, M. Level of Basic Fibroblast Growth Factor in Breast Cancer Patients. Journal of High Institute of Public Health, 1999; 29(4): 725-730. doi: 10.21608/jhiph.1999.325380

Level of Basic Fibroblast Growth Factor in Breast Cancer Patients

Article 8, Volume 29, Issue 4, October 1999, Page 725-730  XML
Document Type: Original Article
DOI: 10.21608/jhiph.1999.325380
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Authors
Ashraf El-Ghandour1; Manal El-Sorady2; Amr Abdelaziz2; Magdy El Bordini3
1Internal Medicine department, Faculty of Medicine, Alexandria University, Egypt
2Clinical Oncology department, Faculty of Medicine, Alexandria University, Egypt
3Clinical Pathology Department, Faculty of Medicine, Alexandria University, Egypt
Abstract
Serum basic fibroblast growth factor (bFGF) was determined before and after surgery in 40 female patients with cancer breast, 20 with no metastasis (group 1) & 20 had metastasis. Sixty percent of group I had elevated bFGF and showed a significant difference before and after surgery, while 80% of group II had elevated bFGF with no significant difference before and after surgery. The mean value of serum bFGF before surgery in group I was 7.64+2.96 and it was 4.91±1.89 after surgery compared 8.56±2.8 & 8.02±2.8 for group II. This indicate that bFGF has a direct relation to the tumor and its metastasis and surgery in non-metastatic tumor may normalized the level of bFGF and its increase may indicate metastasis.
Keywords
Basic Fibroblast; Growth Factor; Breast Cancer; Patients
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